Book Hotels in Santa Isabel
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Top Santa Isabel hotels

Caribbean Paradise – Oceanfront Villa with Infinity Pool & Garden Sanctuary
Santa Isabel PR
This vacation home includes a garden and barbecue grills.
Our stay was absolutely amazing. The property is beautiful and exactly like the pictures. Very clean, comfortable and stocked with every item you could need (keurig, ice maker, utensils, etc.) The pool is perfect and we spent a couple of our entire days just enjoying it. We did not want to leave. ...
Reviewed on Nov 8, 2025

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Santa Isabel Santa Isabel
$409 nightly
The price is $434 total per night from Nov 28 to Nov 29
$434 total
Nov 28 - Nov 29
Total with taxes and fees
This vacation home featured laundry facilities and barbecue grills.
Unforgettable Family Vacation at Mimi’s Stunning VRBO!
Our stay at Mimi’s VRBO was unforgettable, and we’re already planning our return! After searching for the ideal family rental, we chose Mimi’s listing and it was a game-changer. Her warmth and quick responses made everything seamless. When our flight was delayed, Mimi arranged a car to get us to ...
Reviewed on Jun 2, 2025

Hacienda del Sur
Carr 545 KM 1.5, Sector Gabia Santa Isabel
$160 nightly
The price is $175 total per night from Dec 2 to Dec 3
$175 total
Dec 2 - Dec 3
Total with taxes and fees
An outdoor pool is featured at this hotel, along with a virtual front desk. Take advantage of the free self parking.
Perfect stay. Stunning views. Delicous food and great bar on site. Pool was nice. Everything was extremely clean, all staff was amazing. San juan only an hour away, Orocovis is super close to. 10/10 will be staying here again
Reviewed on Sep 7, 2025

Modern Cozy Home in Puerto Rican Paradise
Santa Isabel
Stay at this vacation home in Santa Isabel. Enjoy free WiFi, a water park, and an in-room coffeemaker. Popular attractions Carribbean Cinemas Santa Isabel and ...
Amazing stay
This place was great and got the job done! Clarissa was not only super helpful but she was very accommodating and easy to contact. If we ever are back on that side of the island we will definitely be staying here again.
Reviewed on Apr 10, 2025

Ponce Plaza Hotel & Casino
Reina Street Ponce
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $204 total per night from Nov 30 to Dec 1
$204 total
Nov 30 - Dec 1
Total with taxes and fees
A casino and an outdoor pool are featured at this smoke-free hotel. Enjoy the gym and perks like free WiFi. Self parking, a coffee shop, and a library are also ...
Location and great parking
Reviewed on Nov 19, 2025

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
$341 nightly
The price is $362 total per night from Nov 27 to Nov 28
$362 total
Nov 27 - Nov 28
Total with taxes and fees
A hot tub is featured at this vacation home, along with laundry facilities and concierge services. Barbecue grills are provided for your convenience.
Loved it!!!!! Spacious clean! Internet did not work but to be honest we did not need it at all.
Reviewed on Sep 7, 2025

Hilton Ponce Golf & Casino Resort
1150 Caribe Avenue Ponce
$178 nightly
The price is $197 total per night from Dec 14 to Dec 15
$197 total
Dec 14 - Dec 15
Total with taxes and fees
This luxury resort features a golf course, free water park access, and a casino. Bring the family and enjoy the mini golf, children's pool, and waterslide. Enjoy ...
La habitación estaba impecable. El personal muy atento.
Reviewed on Nov 21, 2025

Aloft Ponce Hotel & Casino
Street No 2 KM 228.9 Ponce
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $159 total per night from Dec 7 to Dec 8
$159 total
Dec 7 - Dec 8
Total with taxes and fees
A casino, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Guests will appreciate free perks like free self parking and WiFi in ...
Everything is good and the staff was very corteous
Reviewed on Nov 17, 2025

Hotel Las Vegas
PR 153, Km 2.9 Santa Isabel
$92 nightly
The price is $100 total per night from Dec 3 to Dec 4
$100 total
Dec 3 - Dec 4
Total with taxes and fees
Free WiFi in public areas is provided and the front desk is staffed around-the-clock.
Good thing Walmart nearby
Reviewed on Nov 5, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Santa Isabel hotel reviews by fellow wanderers

Hilton Ponce Golf & Casino Resort
5 out of 5
Posted 5 days ago
Travelocity Verified Review
"La habitación estaba impecable. El personal muy atento. "
A verified traveler from CAGUAS stayed at Hilton Ponce Golf & Casino Resort
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