Book Hotels in Santa Isabel
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Santa Isabel hotels

Hacienda del Sur
Carr 545 KM 1.5, Sector Gabia Santa Isabel
$141 nightly
The price is $154 total per night from Mar 4 to Mar 5
$154 total
Mar 4 - Mar 5
Total with taxes and fees
An outdoor pool, free self parking, and a virtual front desk are featured at this hotel. A garden is also provided.
This place was so impressive. The grounds are immaculate. The rooms are super clean and Modern. The Pool area is very calming. The food from the bar area was really tasty. Everyone was very nice and accommodating. I will definitely stay there again.
Reviewed on Feb 20, 2026

Caribbean Paradise – Oceanfront Villa with Infinity Pool & Garden Sanctuary
Santa Isabel PR
This vacation home includes a garden and barbecue grills.
It is a very small house it really should not be marketed for more than 4 people the single seat bed is not good for an adult. Once you open de sofa bed there is no space to socialize inside the house. Having a beach front property with a pool and not provide beach towels is not convenient at all. ...
Reviewed on Jan 4, 2026

Ponce Plaza Hotel & Casino
Reina Street Ponce
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $192 total per night from Mar 1 to Mar 2
$192 total
Mar 1 - Mar 2
Total with taxes and fees
A casino and an outdoor pool are featured at this smoke-free hotel. Enjoy the gym and perks like free WiFi. Self parking, a coffee shop, and a library are also ...
Everything was exceptional…very clean, friendly staff, excellent WiFi and a/c, had every amenity we needed.
Reviewed on Feb 25, 2026

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
$334 nightly
The price is $355 total per night from Mar 5 to Mar 6
$355 total
Mar 5 - Mar 6
Total with taxes and fees
Laundry facilities, concierge services, and barbecue grills are available at this vacation home.
Plenty of space, no hot tub on site as advertised. Hot water was tricky needed to turn on myself. Quite a bit of driving to nice swimming beaches. Overall nice place.
Reviewed on Feb 9, 2026

Hilton Ponce Golf & Casino Resort
1150 Caribe Avenue Ponce
Fully refundableReserve now, pay when you stay
$234 nightly
The price is $260 total per night from Mar 18 to Mar 19
$260 total
Mar 18 - Mar 19
Total with taxes and fees
This luxury resort features a golf course, free water park access, and a casino. Bring the family and enjoy the mini golf, children's pool, and waterslide. Enjoy ...
Amazing stay during the week nice and quiet with plenty to do!
Reviewed on Feb 21, 2026

Aloft Ponce Hotel & Casino
Street No 2 KM 228.9 Ponce
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $169 total per night from Mar 8 to Mar 9
$169 total
Mar 8 - Mar 9
Total with taxes and fees
A casino, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy the 24-hour gym and perks like free self parking and free WiFi. ...
Fun hotel is what sticks out the most
Reviewed on Feb 26, 2026

Hotel Las Vegas
PR 153, Km 2.9 Santa Isabel
$79 nightly
The price is $86 total per night from Mar 25 to Mar 26
$86 total
Mar 25 - Mar 26
Total with taxes and fees
Free WiFi in public areas is provided and the front desk is staffed around-the-clock.
Good staff
Reviewed on Feb 25, 2026

Beachfront Bliss: Spacious 5-Bedroom, 2-Bath Escape with Stunning Ocean Views
santa isabel puerto rico
Stay at this villa in Santa Isabel. Enjoy patios and air conditioning. Popular attractions Playa La Ochenta and Marina de Salinas are located nearby.
Place dirty inside and out (windows, beds, sheets, floor, bathroom, etc) AC didn’t work, mold, not enough towels, no wi-fi, Sofa with stain. Cats and dogs around. An the host didn’t answer any type of communication.
Reviewed on Nov 1, 2025

Modern Cozy Home in Puerto Rican Paradise
Santa Isabel
Stay at this vacation home in Santa Isabel. Enjoy free WiFi, a water park, and an in-room coffeemaker. Popular attractions Carribbean Cinemas Santa Isabel and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Santa Isabel hotel reviews by fellow wanderers

Ponce Plaza Hotel & Casino
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Everything was exceptional…very clean, friendly staff, excellent WiFi and a/c, had every amenity we needed. "
A verified traveler stayed at Ponce Plaza Hotel & Casino
Explore More Ways to Travel with Travelocity
- Hotels near El Vigia Hill
- 3 Star Hotels in Isla Caja de Muertos
- Apartments in Isla Caja de Muertos
- Isla Caja de Muertos Hotels
- Vacation Homes in Isla Caja de Muertos
- Resorts in Isla Caja de Muertos
- Villas in Isla Caja de Muertos
- Hotels near San Cristobal Canyon
- Central Aguirre Hotels
- Asomante Hotels
- Jauca I Hotels
- Hotels near Cardona Island Light
- Primero Hotels
- Hotels near Reserva Nacional de Investigación Estuarina de Bahía de Jobos
- Ponce Centro Hotels
- Hotels near Toro Negro State Forest
- Apartments in Juana Diaz
- Extended Stay Hotels in Juana Diaz
- Juana Diaz Hotels
- Motels in Juana Diaz
- Vacation Homes in Juana Diaz
- Villas in Juana Diaz
- Coamo Hotels
- Motels in Coamo
- Orocovis Hotels
- Barranquitas Hotels
- Caonillas Arriba Hotels
- Hotels near Mercedita
- Llanos Hotels
- Hotels near El Museo Castillo Serralles
- Aibonito Hotels
- Coto Laurel Hotels
- Apartments in Salinas
- B&B in Salinas
- Extended Stay Hotels in Salinas
- Salinas Hotels
- Playa Hotels
- Plata Hotels
- Cuarto Hotels
- Villalba Hotels
- Hotels near Marina de Salinas
- Hotels near Albergue Olimpico
- Hotels near La Guancha
- Ponce Hotels
- Flights to Isla Caja de Muertos
- Flights from Chicago to Isla Caja de Muertos
- Flights to Juana Diaz
- Flights from Mercedita
- Jetblue Airways Baltimore (BWI) to Ponce (PSE) flights
- Jetblue Airways Hartford (BDL) to Ponce (PSE) flights
- Jetblue Airways Charlotte (CLT) to Ponce (PSE) flights
- Jetblue Airways Fort Lauderdale (FLL) to Ponce (PSE) flights
- Jetblue Airways Houston (IAH) to Ponce (PSE) flights
- Jetblue Airways Rochester (ROC) to Ponce (PSE) flights
- Jetblue Airways Syracuse (SYR) to Ponce (PSE) flights
- Jetblue Airways Jacksonville (JAX) to Ponce (PSE) flights
- Jetblue Airways New York (JFK) to Ponce (PSE) flights
- Jetblue Airways New York (LGA) to Ponce (PSE) flights
- Jetblue Airways Boston (BOS) to Ponce (PSE) flights
- Jetblue Airways Miami (MIA) to Ponce (PSE) flights
- Jetblue Airways Newark Liberty Intl. Airport (EWR) to Ponce (PSE) flights
- Jetblue Airways Chicago (ORD) to Ponce (PSE) flights
- Jetblue Airways Orlando (MCO) to Ponce (PSE) flights
- Jetblue Airways Philadelphia (PHL) to Ponce (PSE) flights
- Jetblue Airways Raleigh (RDU) to Ponce (PSE) flights
- Jetblue Airways San Antonio (SAT) to Ponce (PSE) flights
- Jetblue Airways Phoenix (PHX) to Ponce (PSE) flights
- Jetblue Airways Fort Myers (RSW) to Ponce (PSE) flights
- Jetblue Airways Tampa (TPA) to Ponce (PSE) flights
- Jetblue Airways Providence (PVD) to Ponce (PSE) flights
- Spirit Airlines Orlando (MCO) to Ponce (PSE) flights
- Flights from Atlanta (ATL) to Ponce (PSE)
- Flights from Hartford (BDL) to Ponce (PSE)
- Flights from Cleveland (CLE) to Ponce (PSE)
- Flights from Dallas (DFW) to Ponce (PSE)
- Flights from Newark Liberty Intl. Airport (EWR) to Ponce (PSE)
- Flights from Fort Lauderdale (FLL) to Ponce (PSE)
- Flights from New York (JFK) to Ponce (PSE)
- Flights from Orlando (MCO) to Ponce (PSE)
- Flights from Philadelphia (PHL) to Ponce (PSE)
- Flights from Raleigh (RDU) to Ponce (PSE)
- Flights from Tampa (TPA) to Ponce (PSE)
- Flights to Salinas
- Car rentals near Isla Caja de Muertos
- Car rental Juana Diaz
- Luxury Car Rentals in Juana Diaz
- Car rental Coamo
- Alamo Rent A Car Rental Cars in Mercedita
- Rental cars Mercedita airport
- Dollar Rent A Car Rental Cars in Mercedita
- Hertz Rental Cars in Mercedita
- Car rental Salinas
- Convertible Car Rentals in Salinas
- Van Car Rentals in Salinas






